Industrial melanism refers to the dark pigmentation that evolved in some insects giving them protective coloration on vegetation darkened by soot in heavily industrialized areas prior to air pollution regulation. Assume that in one heavily polluted area near Birmingham, England in 1956, 79% of the moths of the species Biston betularia were black due to the presence of a dominant gene for melanism. Estimate the frequency of the dominant allele in this population, and the proportion of black moths that are heterozygous.

Explanation:

According to Hardy-Weinberg, the allelic frequencies in a locus are represented as p and q, referring to the allelic dominant or recessive forms. The genotypic frequencies after one generation are p² (Homozygous dominant), 2pq (Heterozygous), q² (Homozygous recessive). Populations in H-W equilibrium will get the same allelic frequencies generation after generation. The sum of these allelic frequencies equals 1, this is p + q = 1.

In the same way, the sum of genotypic frequencies equals 1, this is

p² + 2pq + q² = 1

Being

In the exposed example, 79% of the moths of the species Biston betularia were black due to the presence of a dominant gene for melanism.

If the genotypic frequency of back moths is 0.79, then, by performing the following equation we can get the not-black moths genotypic frequency:

p² + 2pq + q² = 1

where p² is the homozygous dominant genotypic frequency, q² the homozygous recessive genotypic frequency, and 2pq is the heterozygous genotypic frequency.

As 0.79 is the phenotypic frequency of black moths, then this frequency equals p²+2pq.

Clearing the equation:

p² + 2pq + q² = 1

0.79 + q² = 1

q² = 1 - 0.79

q² = 0.21

The genotypic frequency of non-black moths is 0.21. So, from here we can calculate the allelic frequency:

q² = 0.21

q= v 0.21

q = 0.458

If 0.46 is the allelic frequency of non-black moths, then by clearing the equation p + q = 1, we can get the p allelic frequency:

p + q = 1

p + 0.458 = 1

p = 1 - 0.458

p = 0.542

        2 x p x q = 2 x 0.542 x 0.458 = 0.496

Finally, we can check this answer by clearing the following equation:

p² + 2pq + q² = 1

0.294 + 0.496 + 0.21 = 1                  

the answer is b)3/8x+1