explain why prolonged anaeorobic fermatation could cause the enzyme of a cell to become increasingky dysfunctoin and eventually lead to a shutdoen of the cells metabolic pathways

This is end product inhibition. It is a situation in which the product of a reaction inhibits the activities  enzyme that catalysis it formation and therefore  stop the progress  of the reaction.

E.g in Lactic acid fermentation accumulation of lactic acid lowers the pH of the  cells,and therefore affects the active site of the enzymes by disrupting the 3D structure for reactant and enzyme  specificity, and therefore prevent the formation of enzyme=substrate complex, which forms the products

Explanation:

answer; ///i believe the correct answer is (aids) acquired immune deficiency syndrome;

for example, no new evidence will demonstrate that the earth does not orbit around the sun (heliocentric theory), or that living things are not made of cells (cell theory), that matter is not composed of atoms, or that the surface of the earth is not divided into solid plates that have moved over geological timescales .