A disadvantage of using an attenuated live microbe in a vaccine is that it can conceivably mutate back to a virulent strain. a. True
b. False

True

Explanation:

Live attenuated vaccine are vaccines that contain a weakened part of the live virus or bacteria and protect the immune response of people with healthy immune system and does not cause disease.

These type of vaccine create a strong immune response but does not work for people who have weak immune system.

Examples of live attenuated vaccines are,

Rotavirus vaccine

Nasal flu vaccine.

A disadvantage of live attenuated vaccine is that it can conceivably mutate back to a virulent strain,They can cause disease, due to genetic reversion or to infection of immunocompromised hosts.

Another disadvantage is that they are difficult to maintain and stored.