A biologist at World University used Procedure IV to conduct an additional study and found the sequence following below. Using your knowledge of central dogma generate the amino acid sequence that results from this sequence. Given DNA sequence: CAC GAC GGA TTC GTA

Valine-Leucine-Proline-Lysine-Histidine

Explanation:

The central dogma of biology is the process by which DNA is used to synthesize RNA and subsequently amino acid sequence (PROTEIN). The processes of transcription and translation is used in gene expression. Transcription is the process whereby the information encoded in a DNA molecule is used to synthesize a mRNA molecule. Transcription is catalyzed by RNA polymerase enzyme, which uses complementary base pairing rule i.e Adenine(A)-Thymine(T), Guanine(G)-Cytosine(C) pairing.

N.B: Thymine is replaced by Uracil in the mRNA

For the above DNA sequence: CAC GAC GGA TTC GTA, the mRNA sequence will be: GUG CUG CCU AAG CAU

Translation is the second process of gene expression which involves the synthesis of an amino acid sequence from an mRNA molecule. The mRNA is read in a group of three nucleotides called CODON. Each codon specifies an amino acid (see attached image for genetic code)

Based on the attached genetic code, an mRNA sequence: GUG CUG CCU AAG CAU will encode an amino acid sequence: Valine(Val) - Leucine (Leu) -Proline (Pro) -Lysine (Lys) - Histidine (His).

GUG specifies Valine amino acid

CUG specifies Leucine amino acid

CCU specifies Proline amino acid

AAG specifies Lysine amino acid

CAU specifies Histidine amino acid

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