Biochemical signaling that is transduced via the protein tyrosine kinase signal transduction cascade is involved in regulating cell growth and differentiation. Identify one example from the scientific literature of an example of how either structural proteins or enzymes involved in this pathway can used as viable anticancer targets. Please include the reference that you use.

Tyrosine kinases are therapeutic targets for anticancer compounds  

Explanation:

Tyrosine kinases are a type of enzymes capable of activating signaling network pathways by protein phosphorylation, which is a posttranslational modification where one phosphate group is added to the protein and thereby activating it. In the last years, tyrosine kinases have been used as therapeutic anticancer agents. For example, it has been shown that c-MET proto-oncogene, a receptor tyrosine kinase involved in signaling pathways, is targeted by the PROteolysis TArgeting Chimera (PROTAC). PROTAC is a drug that acts as an enzyme capable of removing unwanted proteins bound to this receptor.

d concave shape of wave rock

explanation:

the concave shape of wave rock is a very good evidence that supports the evolution of earth due to chemical weathering. if we talk about structure of   wave rock, studies have estimated that it is around 2.7 billion years old. it also serves as the foundation of evidence that it was the place where australian continent began to form.

how the structure of wave rock was created?

studies suggest that structure of wave rock was created when the surrounded area was started to weather due to which deposition of material started on the part of land which now contains wave rock.

the structure of wave rock is considered to be one of the best-known landforms in australia. at the height of around 15 cm, there can be found flared slopes which formulate the margins of hyden rock. it is now assumed by geologists that wave rock was created by subsurface water-induced weathering and not by glaciers, waves or wind.

due to deposition of material over the period of long time, the wave rock became tougher and tougher due to weathering from surrounding terrain. this makes it a physical evidence that supports   the evolution of earth due to chemical weathering.

hope it !