Which of the following is TRUE about lysosomes? A. They contain enzymes only capable of breaking down nucleic acids. B. They are bound by a single membrane but can engulf organelles containing double membranes. C. Proteins targeted to the lysosome are glycosylated in the ER and a specific mannose is phosphorylated. D. The final, functional state of lysosomal enzymes contains mannose-6-phosphate.