Why does a fever cause a life-threatening problem

The fever is the immune system's attempt to kill the infection. Very rarely, however, this immune response can result in a fever high enough to cause permanent harm or even life-threatening complications due to overheating.

answer; /// i believe the name your looking for is called (plaque)or check good luck

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme