What is the connection between Modus Ponens and confirmation in science? They are not directly related, as modus ponens is used in other reasoning in science than in confirmation. Modus ponens is the schema of confirmation and because modus ponens is a valid form, it is exactly the way confirmation works in science Science is only inductive, so modus ponens is not used in science at all. Modus ponens is used in science only for falsification schema of reasoning.