How doResponse area are proteins that Response area up the rate of a reaction. Enzymes are a type of Response area. The difference between a catalyst and an enzyme is that the enzyme is a Response area and is organic; catalysts do not have to be organic nor do they have to be proteins. An enzyme works by Response area the activation energy of a reaction. Once the reaction occurs, the enzyme is Response area so that it can be used again in other reactions. enzymes make chemical reactions more efficient?