What type of interaction(s) is NOT involved in the binding of a substrate to a normally functioning enzyme

Explanation:

Non covalent bond are mostly involved in the binding of enzyme to active site, example include hydrogen bonds, Ionic bond, hydrophobic interaction and a transient covalent bond.

A permanent covalent bond is usually not involved in the binding of substrate to active site where the reaction rakes place.

covalent bond is a chemical bond, its involves the sharing of electron pairs between atoms. It is mostly used for interraction between metals this is because the bond formed at usually not easily breakable

Options are not given, here are the options.

a. H bonds

b. a transient covalent bond

c. ionic bonds

d. a permanent covalent bond

e. hydrophobic interactions

The correct option is D.

A permanent covalent bond.

Explanation:

A permanent covalent bond is not involved in the binding to a normally functioning enzyme because this bond entail sharing of electron pairs between atoms unequally in a substance and the donor is usually Lewis base or ligand and the acceptor is Lewis acid or central atom.

These bonds are Majorly important in interactions between transition metals and organic ligands like Iron 11 Fe2+ present in hemoglobin and the cytochrome .