The G protein coupled receptor (GPCR) pathway elicits diverse intracellular responses in different cells. The basic steps of GPCR signaling are outlined in this diagram. Which of the following statements correctly describes the process of GPCR signaling?

A) The GPCR activation is reversible after the signal of the ligand diminishes.
B) The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression.
C) The ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway.
D) The ligand-bound GPCR sends a GTP molecule to an enzyme in the membrane and switches it into an active state.

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the principles and empirical processes of discovery and demonstration considered characteristic of or necessary for scientific investigation, generally involving the observation of phenomena, the formulation of a hypothesis concerning the phenomena, experimentation to test the hypothesis, and development of a conclusion that confirms, rejects, or modifies the hypothesis.

for example, no new evidence will demonstrate that the earth does not orbit around the sun (heliocentric theory), or that living things are not made of cells (cell theory), that matter is not composed of atoms, or that the surface of the earth is not divided into solid plates that have moved over geological timescales .