Some signals, like growth factors, affect multiple pathways, activating some proteins and inhibiting others in the course of eliciting specific responses. Ras is an oncogene and over activation of Ras is associated with aggressive tumor growth. Which of the following would be expected in response to a growth signal activating Ras that is sustained?

A) apoptosis first, then cell cycle, then cell growth
B) cell cycle first, then cell cycle arrest, then metabolism
C) metabolism first, then apoptosis, then DNA replication
D) cell growth first, then DNA replication, then cell cycle arrest