30 POINTS! NEED HELP ASAP

The gene that causes sickle-cell disease is present in a higher percentage of residents of sub-saharan africa than among those of african descent living in the united states. even though this gene causes sickle-cell disease, it also provides some protection from malaria, a serious disease that is widespread in sub-saharan africa but absent in the united states. discuss an evolutionary process that could account for the different percentages of the sickle-cell gene among residents of the two regions.

Approximately 90% of all cases of polycystic kidney disease are inherited in an autosomal dominant fashion. the disease is typically related to mutations to genes (pkd1 and pkd2). pkd genes can be found on chromosome 16. the disease occurs in approximately 1: 800 to 1: 1000 people. here is a hypothetical example. the dominant allele d will cause the development of pkd. the recessive allele is known as d. what genotypes would correspond to suffering from pkd? dd, dd what genotypes would correspond to being normal (not suffering from pkd)? dd consider that 1: 1,000 people have pkd in your population of 325million. consider that pkd is inherited in an autosomal dominant fashion. show you math for all of the following questions: what is the genotypic frequency for dd? what is the genotypic frequency for dd? what is the genotypic frequency for dd? what is p? what is q? how many people in your population would have pkd?

20. in humans, freckles are dominant to no freckles. trey has no freckles and his wife anna grace has freckles, but her dad doesn't. they want to know what percentage of their kids would look like trey. show a punnett square to support your answer.