Natural selection disrupts the because one allele of a gene is preferred over another, changing the allele frequencies over time.

genetic drift

Explanation:

Genetic drift is changes in allele frequencies of a gene pool due to chance or random events. This can occur in large or small populations. Genetic drift causes gene pools of two isolated populations to become dissimilar as some alleles are lost and other are fixed.

the answer is true when observing or determining population size, a direct observation is use, in which each organism is counted in a population or in an area. one benefit of this measure is that you get the exact population count but it will take a long time to  determine  the  size  of a  population.