The development of retinoblastoma is associated with a mutation in the 13q14.2 region of the human genome. What is the principle of indexing different parts of the genome?

Genome indexing is a strategy to find a pattern (i.e., a short sequence read) in a long text (i.e., the genome)

Explanation:

Genome indexing is a similar strategy used when a book is indexed. This strategy is used to find more rapidly a given sequence by allowing to align the problem sequence and thus approximate to the putative origin of the query sequence within the genome. Genome indexing enables to design PCR primers/probes, map probes at genome level, understand data obtained from gene expression analyses, etc.

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in which structure in the nucleus are ribosomes made?

b) nucleolus!

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