Help please & thank you.

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme

passive transport is a movement of biochemicals and other atomic or molecular substances across cell membranes without need of energy input. unlike active transport, it does not require an input of cellular energy because it is instead driven by the tendency of the system to grow in entropy.

so, according to what that says, i believe it's hypertonic and hypotonic.

good luck!