Why is caffeine unlikely to cross through the phospholipid bilayer?

Because caffeine is a big polar molecule and it can't pass directly through the phospholypid bilayer so it needs to pass through a channel.

they are c. hope this !

"griffith's experiment discovering the "transforming principle" in pneumococcus bacteria. griffith's experiment, reported in 1928 by frederick griffith, was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation." - griffith's experiment.