Glycogen synthetase kinase 3 beta is a protein kinase that has been implicated in many types of cancer. Depending on the cell type, the gene for glycogen synthetase kinase 3 beta (GSK3β) can act either as an oncogene or as a tumor suppressor. Which of the following best predicts how GSK3β mutations can lead to the development of cancer? A)Cells with inactive GSK3β fail to trigger apoptosis.
B) Cells with inactive GSK3β fail to proceed past the G2/M checkpoint.
C) Cells with overactive GSK3β are more likely to repair DNA damage.
D) Cells with overactive GSK3β have longer cell cycles.