What might be some advantages and disadvantages of using viruses in genetic engineering to treat human diseases?

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Explanation:

The Adenovirus, Adeno-Associated Virus, and the Retrovirus are the most commonly used vectors in gene therapy clinical trials. Results: Disadvantages to using the Adenovirus as the vector in gene therapy include non- integration, immunogenicity, replication competence, no targeting, and small insert size.

Benefits and advantages of using the Adeno-Associated Virus as the vector in gene therapy trials include integration into host genome, no viral genes, able to transduce cells not actively dividing, wide range of host cells, and they are non-inflammatory and non-pathogenic.

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