Punnett squares??

I really don't understand this please help!!

The genotypes would include 2 brown-eyed children, and 2 blue-eyed children.

Explanation:

Punnet Squares are really easy once you get the hang of it, it's a literal square that you match up the genotypes to create a probability of offspring.

x        B          b

b       Bb        bb       Go to a certain square and multiple the top and bottom

b       Bb        bb       variable together!

So there would be 50% brown-eyed children and 50% blue-eyes children!

it marks things for degradation via the proteasome. it alters there celluar location.