By what process do bacteria develop resistents against antibiotics

Antibiotics resistance

Explanation:

Antibiotics resistance refers to a process whereby bacteria eliminate the effectiveness of drug that suppose to cure it's infections but rather had no effect on it and continually grow to such drug.

Bacteria develop resistance to antibiotics by using instructions the DNA provides . The resistance genes are located within plasmids, which is a small pieces or part of DNA that consist of the genetic instructions from one germ to another. This is an indication that some bacteria can actually share their DNA and influence other germs to be resistant to antibiotics that should cure the infections cause by them.

your answer is "the 1950's"