What does the term mutation mean in regards to human genetics?

Which sentence best expresses the differing opinions of these two book reviews?

The tasmanian devil, a marsupial carnivore, is facing extinction due to devil facial tumor disease (dftd) which causes bulging cancerous lumps and lesions to erupt around the face and neck — often causing enough deformation to make seeing or eating difficult. dftd has evolved into a contagious cancer, a trait that is unique among cancers. devil mating behavior involves biting around the head and neck, allowing cells from one individual — especially cells from the crumbly dftd tumors — to be transferred to the wounds or face of a new individual. this marsupial was once found across australia, but sea levels rose, isolating the tasmanian population, while the australian population went extinct. what would be an outcome of genetic isolation that is likely to have impacted the spread of dftd? a) reduced territory puts diseased individuals in greater contact with non-diseased ones. b) inbreeding results in less variation in facial features so the cancer is generally fatal. c) genetic isolation has made it difficult for scientists to develop a vaccine against dftd. d) the lack of genetic variation in the immune system of tasmanian devils minimizes resistance to the disease.

Which is an advantage of having memory cells when a pathogen is encountered for a second time. a) the memory cells are what proliferate into clones of cells in response to the binding of an antigen. b) memory cells are vital to the primary immune response in that they immediately recognize pathogens even at the first encounter. c) memory cells are essentially effector cells that are short lived and attack antigens even without having a receptor specific to that antigen. d) it ensures that more lymphocytes with a receptor specific to a particular antigen will be present than in a host that had never encountered that pathogen.