Albinism in humans can be caused by recessive mutations in different genes that cause a total lack of melanin pigment. A complementation test would be available when two people with albinism mate to produce offspring. If the two people carry mutations in different genes that each cause albinism, what frequency would albinism occur in their children?

none (zero frequency)

Explanation:

The complementation test is widely used in genetics for assessing whether two mutations associated with a phenotypic trait represent two different gene variants of the same gene (i.e., two alleles of the same gene) or if they are mutations associated with two different genes. In a recessive trait, the offspring must receive one recessive allele from each parent in order to show the recessive phenotype (in this case, albinism). Moreover, in heterozygous individuals for a trait that exhibits complete dominance, recessive alleles always are masked by dominant alleles. Albinism is a multigenic (polygenic) recessive trait, thereby individuals who carry recessive mutations causing albinism on different genes will have zero probability (none) of having offspring with albinism.

albinism frequency ---> 3/4 = 75% = 0.75 of the progeny will be albino.

Explanation:

Available data:

Let us say that genes A and B are involved.

Cross:  two people with albinism that carry the mutation in different genes

Parentals) Aabb    x    aaBb  

Phenotype) Albino both parents

Gametes) Ab, Ab, ab, ab  

                aB, aB, ab, ab

Punnett square)    Ab         Ab         ab         ab

                    aB    AaBb     AaBb    aaBb    aaBb

                    aB    AaBb     AaBb    aaBb    aaBb

                    ab    Aabb      Aabb    aabb    aabb

                    ab    Aabb      Aabb    aabb    aabb

F1) 12/16 will be albino

     4/16 will express color

     4/16 will be Aabb

     4/16 will be aaBb

     4/16 will be aabb

12/16 = 3/4 = 75% = 0.75 of the progeny will be albino.

d statement

explanation: