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Biology, 23.03.2021 04:40 camiilajakobsen1400

The use of short Okazaki fragments in the lagging strand of DNA replication bubble: Overcomes the problem of phosphodiester bond formation requiring energy. Overcomes the requirement by the DNA polymerase for a free 5' OH. Overcomes the problem of having to ligate the DNA strands after DNA replication is finished. Overcomes the problem of two replication forks colliding when termination of bidirectional DNA replication occurs Overcomes the problem of requiring that the DNA polymerase synthesize the lagging strand in the opposite direction (3' to 5') to that of the leading strand (5' to 3').

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