Sickle-cell disease is a disorder that results in malformed hemoglobin molecules. What is the result of this in terms of hemoglobin function? Multiple Choice Hemoglobin has a reduced ability to bind to and transport oxygen in red blood cells. Hemoglobin has an increased ability to bind to and transport oxygen in red blood cells. Hemoglobin has an increased ability to bind to and transport carbon dioxide in red blood cells. White blood cells begin to pick up hemoglobin molecules instead and this decreases their ability to function in the immune system as intended.