In a real cell, what does the dna molecule do before it unzips?

I'm not sure if i fully understood your question but i'll go ahead and answer it .. The DNA molecule has the promotor region which is detected by the transcription factors that are responsible to start transcription ( and hence , unzipping the dna strands ) 

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Na+ loss through sweet plus the dilution has lowered na+ concentration outside of neurons, altering the na+ equilibrium potential. sodium exists more outside the cells than inside. when na+ is lost by sweat plus the dilution( because they drink a lot of water) changes the concentration outside the cell, forcing the water to enter the cell and attempt to balance the concentration inside/outside.the problem is that the abundance of water will cause the cells to swell. most cells can adapt, however, the brain cells can't that's why the runner has confusion and can't control the muscles.  if not treated and this occurs in less than 48 hours, it can be immediately fatal .