How does the endocrine system respond to hunger

Have you ever caught yourself mindlessly eating with little awareness of hunger, only to realize that “handful” of crackers turned into the entire box? Alternatively, perhaps you have ever been so caught up in your busy day that you forgot to eat altogether, only to suddenly discover you were absolutely ravenous? If so, then you have experienced the sometimes puzzling effects of specialized signaling molecules in the body, formally referred to as “the hormones of appetite and satiety.”There is a significant correlation between these recently identified hormones and how the gut communicates with the brain to regulate weight. This relationship is currently the subject of intensive new research (mostly on mice) with researchers and field experts digging for clues that will help people quickly lose excessive weight, while keeping it off for good.

Where are they though?