How does altitude affect climate?

the higher the altitude, the colder the climate will be
the lower the altitude, the colder the climate will be
the higher the altitude, the hotter the climate will be
altitude is not related to climate

me find out which one is

it would be heredity

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products