Which substance can enter a cell by diffusion without having to be digested

Which statement describes john tuzo wilson’s contribution to the theory of plate tectonics?

The nervous system interacts with the endocrine system by a. using hormones as connections b. sending nerve impulses directly to glands c. using neuroendocrine cells as connections d. sending neurotransmitters directly to neurons

Which is one example of a phenotypic change that is not genetic