The health determinant which we have least control over is

i believe it is "they are not used up by reactions" as the answer to your question, text me back if this is correct because i just learned this.

you didn't give any options but heres what i can tell you: an inference is likely to change based on additional observations. the latter is something that you have seen or sensed using your sensory organs while the former is like a conclusion out from what you have observed.