PLEASE HELP ASAP 2.) A person with Down syndrome has an extra copy of chromosome 21. What can you infer is most likely the genetic mutation that results in Down syndrome?

Nondisjunction during meiosis
Complete duplication of chromosomes during polyploidy
Translocation during genetic replication
Crossing over during meiosis

Of seawater increases with decrease in the temperature. therefore, the cold water sinks to the deeper layers at the bottom

Plz will mark! the diagram shows the positions of the sun, moon and earth during spring tides, when the high tides are at their highest and low tides at their lowest. what is it about these positions that causes these high and low tides?

To answer this question, researchers studied populations of the dusky salamander (desmognathus ochrophaeus) living on different mountain ranges in the southern appalachian mountains. the researchers tested the reproductive isolation of pairs of salamander populations by leaving one male and one female together and later checking the females for the presence of sperm. four mating combinations were tested for each pair of populations (a and b)—two within the same population (female a with male a and female b with male b) and two between populations (female a with male b and female b with male a). the proportion of successful matings for each mating combination was measured. for example, when all the matings of a particular combination were successful, the researchers gave it a value of 1; when none of the matings were successful, they gave it a value of 0. then the researchers calculated an index of reproductive isolation that ranged from 0 (no isolation) to 2 (full isolation). the reproductive isolation value for two populations is the sum of the proportion of successful matings of each type within populations (aa + bb) minus the sum of the proportion of successful matings of each type between populations (ab + ba). the table provides data for the geographic distances and reproductive isolation values for 27 pairs of dusky salamander populations.