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Biology, 08.05.2021 05:10 Tracic1972

The Arg genes that encode the enzymes for arginine biosynthesis are located at several positions around the genome of E. coli, and they are regulated coordinately by a transcription regulator encoded by the ArgR gene. The activity of the Arg R protein is modulated by arginine. Upon binding arginine, ArgR alters its conformation, dramatically changing its affinity for the DNA sequences in the promoters of the genes for the arginine biosynthesis. A. Given that ArgR is a repressor protein, would you expect that ArgR would bind more tightly or less tightly to the DNA sequences when arginine is absent?

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