Why are sodium ions differentially permeable?

In most cases, an ion channel is permeable only to specific types of ions (for example, sodium and potassium but not chloride or calcium), and sometimes the permeability varies depending on the direction of ion movement.

Explanation:

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Explanation:

This transporter ejects 3 sodium ions from the inside of the cell for every 2 potassium ions it transports in, all against a concentration gradient. ... If, however, membranes are differentially permeable to the ions, an electrical potential across the membrane can arise.

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