Which of the following best describes the role IκBα phosphorylation plays in the signaling pathway and what the modification of IκBα does? IκBα activates the transcription factor. Phosphorylation of IκBα leads to phosphorylation and activation of the transcription factor.
IκBα inhibits the activation of the transcription factor. Phosphorylation of IκBα signals for the nuclear transcription factor to transcribe DNA.
IκBα inhibits the translocation of the transcription factor. Phosphorylation of IκBα signals for IκBα degradation and allows the transcription factor to enter the nucleus.
IκBα activates the translocation of the transcription factor. Phosphorylation of IκBα leads to phosphorylation of the transcription factor, which allows the transcription factor to enter the nucleus.