What leads to the change in shape of the active site when temperature increases? A. increase in temperature, means more molecular collisions at the active site

B. Hydrogen bonds between the amino acids break

C. different amino acids in the enzyme

A

Explanation:

Proteins are chains of amino acids joined end to end. ... This structure is held together by weak forces between the amino acid molecules in the chain. High temperatures will break these forces. The enzyme, including its active site, will change shape and the substrate no longer fit.

B. Hydrogen bonds between the amino acids break

Explanation:

Proteins are chains of amino acids joined end to end. ... This structure is held together by weak forces between the amino acid molecules in the chain. High temperatures will break these forces. The enzyme, including its active site, will change shape and the substrate no longer fit.

rain is the best answer