How does the chain of amino acids determine the shape of a protein?

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Explanation:

A protein's shape is determined by the sequence of amino acids that make up the protein. The order of the amino acids, or the primary structure, determines the folding of the amino acid chains or tertiary structure. The interactions between the side chains and the amino acids determine the folds of the protein. and The primary structure of a protein — its amino acid sequence — drives the folding and intramolecular bonding of the linear amino acid chain, which ultimately determines the protein's unique three-dimensional shape. ... The final shape adopted by a newly synthesized protein is typically the most energetically favorable one.