Biology, 05.07.2021 19:20 srtdklug2005
The concentration of a particular protein X in a normal human cell rises gradually from a low point, immediately after cell division, to a high point, just before cell division, and then drops sharply. The level of its mRNA in the cell remains fairly constant throughout this time. Protein X is required for cell growth and survival, but the drop in its level just before cell division is essential for division to proceed. You have isolated a line of human cells that grow in size in culture but cannot divide, and on analyzing these mutants, you find that levels of X protein do not decrease. Which of the following mutations could explain these results?
a. A mutation that results in the loss of an enzyme that adds a ubiquitin tag to the protein.
b. a mutation in gene X that results in the loss of polyA addition to its mRNA
c. a mutation in gene X that changes the sequence that encodes sites at which ubiquitin can be attached to the protein
d. Both A and C
Answers: 2
Biology, 22.06.2019 10:30
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Transposon can cause mutations in genes at or near the site of transposon insertion. it is possible for these elements to transpose away from their original site, causing a reversion of the mutant phenotype. in some cases, however, even more severe phenotypes appear when these elements excise from this site, due to events at or near the mutant allele. what might be happening to the transposon or the nearby gene to create more severe mutations?
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The concentration of a particular protein X in a normal human cell rises gradually from a low point,...
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