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Biology, 15.07.2021 20:10 Silkyruthie

In humans, an MN blood group system is under control of an autosomal locus found on chromosome 4, with two alleles designated L^M and L^N. The blood type is due to a glycoprotein present on the surface of red blood cells, which behaves as a native antigen, like the better known ABO system. Phenotypic expression at this locus is codominant because an individual may exhibit either one or both antigenic substances. Frequencies of the two alleles vary widely among human populations. Given the following genotypes for a sample of MN blood group on chromosome 4:Genotypes Numbers Observed freq. Expected freq. Expected Number (O-E)2/EMM 144MN 201NN 114A) fill in the table above, what are the predicted genotype numbers for this population if you assume hardy -weinberg conditions? Also estimate allele frequencies and heterozygosity. Part B) does this population deviate from H-W equilibrium (test by chi-square) Part C) consider how you would approach this problem in part B is M was dominant to N and therefore phenotypes yo could record would be just: MM + MN 345 and NN 114You can still estimate the allele frequencies assuming the population is in Hardy-Weinberg equilibrium becaues you kknow the frequency of q^2. Compare to estimate in part B. Which is more accurate and why.

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