Biology, 08.08.2021 08:40 angela563

Describe 2 limitations of a 3D cell model.

Will mark brainliest!!!

Answers: 1

Show answers

Answers

Traditional Pathology: Traditional pathology involves removing cell culture models from well plates and processing them. Despite the fact that this method may obtain pathological information from tissues, the scale of these models makes the process extremely low-throughput, time-consuming, and costly.

Dissolution Based Assays: Many researchers are currently using dissolution based assays where cell culture models are homogenized and analyzed using a fluorescence probe such as Promega’s CellTiter-Glo Luminescent kit. While these assays are high-throughput, they do not capture the 3D data held within these models which makes them intrinsically more valuable than traditional 2D cell culture models.

Answer from: veroushkarose7326

3D structures is the fact that “spheres” can be formed, not from a single cell, but from a few cell clusters. However, even structures created as aggregates of several cells still have a three-dimensional form and seem to be a better model than flat, adherent cultures

Explanation:

Answer from: jg333

Until recently, the investigation of the molecular mechanisms, involved in the response of tumor cells to various anti-tumor agents, were performed on cells grown on two-dimensional (2D) surfaces. The cells cultured on a 2D flat-surface, usually made of polystyrene, do not grow similar to natural conditions, and this affects the cell-to-cell interactions, the cell behavior, and response to different external stimuli [2][3][4]. Thus, developing the new cell culture models to better reflect the chemosensitivity of carcinoma cells to anti-tumor drugs is in high demand. The three-dimensional (3D) culture systems were envisaged to mimic the in vivo situation and create a close to the native environment in which the cells grow and interact with their neighbors and with the surrounding matrix components in all three dimensions like the cells do in the tissue microenvironment.

Answer from: Quest

explanation:

idk

Answer from: Quest

I'm sorry to hear that. i will try to answer your other questions if it is within my ability. : )answers: my favourite colour is black.my favourite food is pasta.my favourite school subject is english, but i do also like lunch time.my least favourite subject is history as well as geography. i have currently garnered a quite equal hatred for both of the subjects.what about you? well, you for the points. : )

Another question on Biology

Biology, 22.06.2019 04:50

Waianapanapa beach in hawaii is a black-sand beach that was formed by waves crashing against volcanic rock. the sand can be very hot on sunny days. which statement best explains why? o a. the black sand has no heat capacity. b. the black sand absorbs no radiation. o c. the black sand is immune to insolation. d. the black sand has a low albedo.

Answers: 1

Answer

Biology, 22.06.2019 07:00

The distant ancestors of tigers may have had bodies without stripes. use the theory of natural selection to explain how tigers may have evolved to have stripes.

Answers: 1

Answer

Biology, 22.06.2019 09:30

Which statement is a physical property? becomes moldy quicklyeasy to digestconducts electricity poorlydoes not burn

Answers: 1

Answer

Biology, 22.06.2019 09:30

How energy flows through each level in this energy pyramid. is all the matter and energy from one level transferred to the next level?

Answers: 1

Answer

You know the right answer?

Describe 2 limitations of a 3D cell model.

Will mark brainliest!!!...