The activation of the serine/threonine protein kinase Akt requires phosphoinositide 3-kinase (PI 3-kinase) to: a. activate the RTK.
b. create phosphorylated lipids that serve as docking sites that localize Akt to the plasma membrane.
c. directly phosphorylate Akt.
d. to create DAG

Mitochondria is the cell organelle that produced the energy that is needed in the body system in form of atp, that is why it is called the power house of the cell. energy is needed by the living organisms to carry out the activities which sustain life.  if the mitochondria is destroyed atp will not be produced. if the mitochondria is destroyed, energy production will stop and the affected living organism will not have the energy to carry out the necessary life processes; this will lead to the death of the organism.

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