The discovery that only the E1 subunit of the PDH complex has lower than normal activity has led you and the medical examiner to assay the concentrations of several key vitamins in various tissues. Assay results Riboflavin and niacin levels are at the low end of the normal range. Thiamine levels are nearly undetectable. Lipoic acid and pantothenic acid levels are at the low end of the normal range. The PDH complex requires the cosubstrate CoA as it converts pyruvate to acetyl CoA. What other cofactors or cosubstrates does the pyruvate dehydrogenase complex require to function

This is s cute awee : (( . well if she's showing you signs that she may like you , then shoot your shot ! don't be afraid . & if you're unsure that she's giving you these signs , then wait out for a little bit . most girls are different . some may act really sweet , but only bc you're a good friend of hers . that , or she might like you . you just never know . but i think you should sit down with her & tell her how you feel . but don't be awkward & shy . just be straight up & tell her how you feel . if the feelings aren't mutual , then don't cry about it . you need to respect her decision & look for others in the world . feelings can be difficult & confusing , but don't be afraid to show them . i say you play it out & if you're still unsure about it , talk to her . - rach