How could epistasis constrain genetic change by natural selection?

lysosomes contain a variety of enzymes, enabling the cell to break down various biomolecules it engulfs, including peptides, nucleic acids, carbohydrates, and lipids (lysosomal lipase). the enzymes responsible for this hydrolysis require an acidic environment for optimal activity. hope i !

b is dominant over the allele for the white fur.

. ph changes the ability of them he enzyme to dissolve in water.