Match the targets in groups 1 and 2 to identify the main functions of the membrane proteins and identify some components associated with the plasma membrane: I.
a

-
b

-
c

I.
d

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e

-
f

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g

-
h

-
i

A.
fibers of extracellular matrix (ECM)

B.
enzymatic activity

C.
intercellular junctions

D.
microfilaments of cytoskeleton

E.
signal reception and relay

F.
transport

G.
cell-celll recognition

H.
attachment to ECM and cytoskeleton

I.
phospholipid bilayer

Although the basic structure of biological membranes is provided by the lipid bilayer, membrane proteins perform most of the specific functions of membranes. It is the proteins, therefore, that give each type of membrane in the cell its characteristic functional properties. Accordingly, the amounts and types of proteins in a membrane are highly variable. In the myelin membrane, which serves mainly as electrical insulation for nerve cell axons, less than 25% of the membrane mass is protein. By contrast, in the membranes involved in ATP production (such as the internal membranes of mitochondria and chloroplasts), approximately 75% is protein. A typical plasma membrane is somewhere in between, with protein accounting for about 50% of its mass.

Because lipid molecules are small compared with protein molecules, there are always many more lipid molecules than protein molecules in membranes—about 50 lipid molecules for each protein molecule in a membrane that is 50% protein by mass. Like membrane lipids, membrane proteins often have oligosaccharide chains attached to them that face the cell exterior. Thus, the surface that the cell presents to the exterior is rich in carbohydrate, which forms a cell coat, as we discuss later.

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