If granite were subjected to intense heat and pressure it would most likely change to

Gneiss is what happen when a granite is put into high pressure temperature, during the Permian period, sedimentary bedrock in the Appalachian region was subjected to high temp and pressure. Rocks which contain many minerals ex: granite is called polymineralic. 

answer; the tunica intima also called tunica interna, consists of elastic fibers,connective tissue and smooth muscle cells;

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products