Which two organ systems regulate homeostasis in our bodies?
nervous and endocrine
cardiovascular and respiratory
nervous and cardiovascular

nervous and endocrine
These two systems are the major organ systems that mainly regulate, communicate, and control the entire body systems and sometimes they become inter-relational.

Its not actually just one system if you look at it, there are various interdependent system that actually manages every movement of every system in order to maintain homeostasis, plainly every set function is a coordinated body system response. For example, the digestive system digests food because of the enzymes and the cells and organs present in its system but again, this is aided by the different hormones which is part of the endocrine system, interdependently. Thus eventually, the circulatory system is the organ system that intiates in dissemination of the different processed and intially metabolized nutrients in the digestive system and sent throughout the body. Incidentally, also the immune system acts as agent in again many systems to maintain the so-called homeostasis. 

Ha ha it happens bro