What is cancer and how does it relate to the cell cycle? 2. what are proto-oncogenes and tumor suppressor genes, and how do they contribute to cancer? 3. what are some things that might make a person have a higher risk of developing cancer? 4. what are some of the major steps that occur in the progression from a single cancer cell to a tumor and then to many tumors spreading throughout the body? 5. as tumors grow and spread, the cells undergo a number of changes. how might the cells in a late stage tumor be different from the original cell that became cancerous? 6. why are different types of cancers named based on where in the body they originate (breast cancer, skin cancer, bone cancer, why does it matter from which organ or tissue type the cancer developed?