Why is using antimicrobial drugs to kill large numbers of gram-negative bacteria in a short period of time a cause for medical concern?

Gram-negative bacteria if used in short period of time causes medical concern because Dead Gram-negative cells, their work is to release lipid A then causing fever and some different medical problems.

Gram-negative bacterias are termed as bacteria which do not retain violet crystal stain which is being used in gram-staining differentiation bacteria method.

They are being found on all examples of gram-negative bacteria. For example,  model organisms and pathogenic bacteria.

because the light is a great source of energy for the plants to survive. (i hope this )

affects the water bodies: excessive use of fertilizers causes eutrophication. the fertilizers which are used on plants affect the quality of land on which it is used, further causing erosion of soil. the fertilizers used on plants contain harmful chemical fumes which affect the environment.