Which of the following events could cause pyruvate and lactate to accumulate in the blood of individuals with pdcd? a. inhibitors of enzymes that process pyruvate into acetyl coa constantly circulate in the blood. b. a mutation causes a defect in one of the three enzymes that processes pyruvate into acetyl coa. c. enzymes responsible for breaking down pyruvate and lactate are under strong feedback inhibition by pyruvate. d. enzymes that process pyruvate into acetyl coa are produced in insufficient amounts.