Mepolizumab and reslizumab improve asthma control by binding to

Interleukin-5 (IL-5). IL-5 is responsible for the recruitment and maturation of eosinophil. Eosinophils on the other hand are majorly involved in the inflammatory response in asthma- characterised by narrowing of the airways. Mepolizumab and reslizumab are, therefore, anti-IL-5

Where’s the selection?

answer: - b cells

explanation: -

there are many types of white blood cells present in our body. one such class of white blood cells are the lymphocytes. the b cells belong to the lymphocyte class of wbcs. the b cells perform their action against the pathogen by producing specialised proteins called as antibodies. these antibodies are produced as and when the b cells encounter pathogens in response to the antigens present on the surface of the pathogen. these antibodies bind to the antigens present on the pathogen and then, target them for destruction by other cells of the immune system.

so, the b cells mediate their action by identifying the antigens present on the surface of the pathogens and then producing antibodies in return to mediate its effect.