What are some factors that would promote the gtowth of a town into a large city?

Some of the factors are:
-Moderate climate. 
-central geography,
-ease of transportation,
 -highways,
-railroads,
-location near a large body of water

Large cities tend to develop far from cities that had either too hot or too cold temperature. It also must be easily accessible by other regions and provide the people with necessary resources that help them sustain their living (such as water, food crops, woods, etc)

Atp is is our little "pocket" of energy. of course, if you have too little, then it means you have too little energy, and you'll pass out. the way to not have enough, is to have no energy sources (glucose, fats, proteins). you can't have too many atp molecules. cycles like the krebs cycle produce it, but if you have too much of any substrate (or too little for that matter), the cycle stops and atp is no longer made (it stops until substrate levels are such that the process can go on). in any case, this is unlikely since atp is constantly hydrolyzed and remade, even while you're asleep. you won't have too much. if you have zero, you are dead or dying.